UW neuroscientists led by Su-Chun Zhang found that neurons derived from stem cells can connect with native neurons and restore motor functions. But more research is needed to translate the findings from mice to people.
The research team is now working to obtain FDA approval for a first human clinical trial to treat devastating injuries in musculoskeletal tissues.
In light of the 20th anniversary of James Thomson’s derivation of human embryonic stem cells, we had some questions for one of the founders of stem cell neuroscience.
“We very quickly became perhaps the top institution in the country in the stem cell engineering area,” says a leading UW researcher. “That was a field that didn’t exist, and we built it.”
New techniques have produced, for the first time, functional arterial cells at both the quality and scale to be relevant for disease modeling and clinical application.
Scientists from the Morgridge Institute for Research and UW-Madison are studying whether stem cell differentiation rates can be accelerated in the lab and made available to patients faster.
The prospect of regenerating bone lost to cancer or trauma is a step closer to the clinic.
The prospect of creating artery “banks” could transform treatment of many common heart and vascular ailments. But it’s a big leap from concept to reality.
The promise of stem cells to treat cardiovascular disease may soon be a step closer to overcoming the last big hurdle before trials in human patients.
Su-Chun Zhang and co-first authors Yuejun Chen and Man Xiong grew the specialized nerve cells from human embryonic stem cells.