A drug typically prescribed for arthritis halts brain-damaging seizures in mice that have a condition like epilepsy, according to researchers at UW–Madison. If the drug proves viable for human patients, it would be the first to provide lasting relief from seizures even after they stopped taking it.
Health & Wellness
Human stem cell-derived heart cells are safe in monkeys, could treat congenital heart disease
Regenerating tissue to support healthy heart function could keep hearts beating stronger and longer, and this is where stem cell research is stepping in.
Study identifies promising target for treating inflammatory bowel disease and colitis-induced colorectal cancers
Researchers uncovered a previously unknown function of a protein that is central to gut health and implicated in the development of colitis, a severe and chronic form of IBD.
Mice eating less of specific amino acid — overrepresented in diet of obese people — live longer, healthier
A calorie may not be just a calorie according to new research from the University of Wisconsin School of Medicine and Public Health.
Relieving stress in insulin-producing cells protects against Type 1 diabetes
Researchers hope that their findings, published today in the journal Cell Metabolism, may point to a potential new treatment that could be administered very early in the development of diabetes.
New drug delivery method harnesses clotting to target anti-cancer drugs at tumors
Researchers found that in mice that received the engineered proteins via intravenous injections, the proteins led to clot formation almost exclusively within tumors, with only very limited thrombosis occurring elsewhere.
UW researchers identify cell type that could be key to preventing marrow transplant complication
UW researchers at the Carbone Cancer Center have identified the cells that can cause graft-versus-host disease, the most common complication of bone marrow transplants.
New nanocapsules deliver therapy brain-wide, edit Alzheimer’s gene in mice
UW researchers have found a way to move gene therapies through the blood-brain barrier, a crucial step for brain-wide CRISPR treatments of disorders like Alzheimer’s and Parkinson’s disease.
Probiotic ‘backpacks’ show promise for treating inflammatory bowel diseases
UW researchers demonstrate just how much promise some well-equipped bacteria hold for improved inflammatory bowel disease treatments.
Brain-gut connection may reveal way to prevent cocaine addiction
Cocaine disrupts the balance of microbes in the guts of mice, part of a cycle of waxing and waning neurochemicals that can enhance the drug’s effects in the brain. But the same chemicals may also be harnessed to prevent addiction, according to new research.