UW researchers at the Carbone Cancer Center have identified the cells that can cause graft-versus-host disease, the most common complication of bone marrow transplants.
animal research
New nanocapsules deliver therapy brain-wide, edit Alzheimer’s gene in mice
UW researchers have found a way to move gene therapies through the blood-brain barrier, a crucial step for brain-wide CRISPR treatments of disorders like Alzheimer’s and Parkinson’s disease.
Probiotic ‘backpacks’ show promise for treating inflammatory bowel diseases
UW researchers demonstrate just how much promise some well-equipped bacteria hold for improved inflammatory bowel disease treatments.
Brain-gut connection may reveal way to prevent cocaine addiction
Cocaine disrupts the balance of microbes in the guts of mice, part of a cycle of waxing and waning neurochemicals that can enhance the drug’s effects in the brain. But the same chemicals may also be harnessed to prevent addiction, according to new research.
Study shows differences between brains of primates — humans, other apes and monkeys — are small but significant
The cellular differences between these species may illuminate steps in their evolution and how those differences can be implicated in disorders, such as autism and intellectual disabilities, seen in humans.
Wild primate virus has pandemic potential should it jump the species barrier, shows study
New research demonstrates the potential for a family of viruses in African primates to jump the species barrier to humans.
Monitoring an invasion: Where are jumping worms now?
Invasive jumping worms threaten soil health in Wisconsin, including in Dane County where the population has infested the University of Wisconsin–Madison Arboretum. Brad Herrick leads crews of volunteers to survey for the worms so that researchers can study their movements and possibly find ways to halt their spread.
New study allows scientists to test therapeutics for rare disease affecting young children
The team used CRISPR gene editing technology to create in rat embryos the mutations that lead to HSP. This allowed them to study how the disease progresses from early development and monitor the progression of symptoms after birth.
Avian influenza persists as migration peaks
The persistence of highly pathogenic avian influenza in wild and domestic birds through the summer months points to a likely rise in cases this fall, according to Wisconsin Veterinary Diagnostic Laboratory Director Keith Poulsen.
Creating stem cells from minipigs offers promise for improved treatments
A new study from Wan-Ju Li’s lab in the UW–Madison Stem Cell & Regenerative Medicine Center advances research into reparative osteoarthritis therapies using stem cells derived from the ears of miniature pigs.