A drug typically prescribed for arthritis halts brain-damaging seizures in mice that have a condition like epilepsy, according to researchers at UW–Madison. If the drug proves viable for human patients, it would be the first to provide lasting relief from seizures even after they stopped taking it.
School of Medicine and Public Health
All creatures great and small: Sequencing the blue whale and Etruscan shrew genomes
Size doesn’t matter when it comes to genome sequencing in the animal kingdom, as a team of researchers at the Morgridge Institute for Research recently illustrated when assembling the sequences for two new reference genomes — one from the world’s largest mammal and one from one of the smallest.
Mice eating less of specific amino acid — overrepresented in diet of obese people — live longer, healthier
A calorie may not be just a calorie according to new research from the University of Wisconsin School of Medicine and Public Health.
Combining cell types may lead to improved cardiac cell therapy following heart attack
A new study from researchers at the University of Wisconsin–Madison and Academia Sinica of Taiwan points to an improved method for regenerating heart muscle following a heart attack.
Mixing donor and recipient immune systems creates tolerance of transplanted kidneys
Specialists at UW–Madison and Stanford University have developed the new approach to kidney transplantation that could one day help recipients tolerate a new organ without the need for anti-rejection medications.
New nanocapsules deliver therapy brain-wide, edit Alzheimer’s gene in mice
UW researchers have found a way to move gene therapies through the blood-brain barrier, a crucial step for brain-wide CRISPR treatments of disorders like Alzheimer’s and Parkinson’s disease.
Brain-gut connection may reveal way to prevent cocaine addiction
Cocaine disrupts the balance of microbes in the guts of mice, part of a cycle of waxing and waning neurochemicals that can enhance the drug’s effects in the brain. But the same chemicals may also be harnessed to prevent addiction, according to new research.
Wild primate virus has pandemic potential should it jump the species barrier, shows study
New research demonstrates the potential for a family of viruses in African primates to jump the species barrier to humans.
Biodegradable gel boosts immune system’s attack on several cancers in mice
The gel, tested in mice, releases drugs and special antibodies that simultaneously deplete immune-blocking cells called macrophages from the surgical site and activate T cells so they can attack cancer.
Seizures and memory problems in epilepsy may have a common cause
A new study could lead to earlier diagnosis of epilepsy and possibly new ways to treat epilepsy and other disorders that share symptoms, like Alzheimer’s disease, traumatic brain injury and autism spectrum disorder.