These sorts of studies cannot be performed in humans, hence the need to develop and study mouse models.
health & medicine
New strategy could yield more precise seasonal flu vaccine
The new approach would better forecast the naturally occurring mutations that help seasonal flu virus dodge vaccines.
Gene regulatory mutation linked to rare childhood cancer
This basic knowledge of a specific cancer is essential to start drug testing, says researcher Peter Lewis.
Cell transplant treats Parkinson’s in mice under control of designer drug
Su-Chun Zhang and co-first authors Yuejun Chen and Man Xiong grew the specialized nerve cells from human embryonic stem cells.
Experimental drug cancels effect from key intellectual disability gene in mice
“We are a long way from declaring a cure for fragile X, but these results are promising,” says researcher Xinyu Zhao.
Wisconsin researchers transform common cell to master heart cell
If replicated in human cells, the feat could one day fuel drug discovery, powerful new models for heart disease and the raw material for treating diseased hearts.
UW–Madison researchers begin work on Zika virus
Very little is known about the virus even though more than 50 years have passed since it was discovered in the Zika Forest in Uganda.
Researchers home in on why female newborns are better protected from brain injury
A protein found in the brains of mice is present at higher levels in females, which offers them stronger protection against one type of injury.
Pluripotent stem cells offer blood ready for preclinical trials
When the body has a low blood cell count, it can have trouble fighting off infection. But transfusible blood products may be in the not-so-distant future.
Lung cell found to act as sensor, regulator of immune response
The cells are implicated in a wide range of human lung diseases, including asthma, pulmonary hypertension, cystic fibrosis and sudden infant death syndrome, among others.