The team used CRISPR gene editing technology to create in rat embryos the mutations that lead to HSP. This allowed them to study how the disease progresses from early development and monitor the progression of symptoms after birth.
Campus news
Avian influenza persists as migration peaks
The persistence of highly pathogenic avian influenza in wild and domestic birds through the summer months points to a likely rise in cases this fall, according to Wisconsin Veterinary Diagnostic Laboratory Director Keith Poulsen.
Chancellor Mnookin tours dairy farm, highlights research efforts
The visit to two dairy farms highlighted the Dairy Innovation Hub, a partnership that conducts research and offers support to Wisconsin’s dairy industry.
How a small, unassuming fish helps reveal gene adaptations
New UW–Madison research sheds light on the genetic basis by which stickleback populations inhabiting ecosystems near each other developed a strong immune response to tapeworm infections, and how some populations later came to tolerate the parasites.
See-through zebrafish, new imaging method put blood stem cells in high-resolution spotlight
This new technique will aid researchers as they develop therapies for blood diseases and cancers.
New injectable gel offers promise for tough-to-treat brain tumors
UW–Madison researchers have developed a powerful immunity-boosting postoperative treatment that could transform the odds for patients with glioblastoma.
New understanding of ‘superantigens’ could lead to improved staph infection treatments
Researchers at the UW School of Veterinary Medicine explain that the bacterium Staphylococcus aureus not only causes illness, but undermines the body’s ability to heal — a finding that could point toward new approaches to fighting infection.
Experimental COVID-19 vaccine provides mutation-resistant T cell protection in mice
A second line of defense — the immune system’s T cells — may offer protection from COVID-19 even when vaccine-induced antibodies no longer can, according to new research out of the University of Wisconsin School of Veterinary Medicine.
UW Veterinary Care offers rabbit vaccine against highly contagious, fatal disease
The clinic is one of about a dozen animal hospitals in the state to offer the vaccine and part of a growing effort nationally to encourage rabbit owners to seek vaccination.
Biodegradable gel boosts immune system’s attack on several cancers in mice
The gel, tested in mice, releases drugs and special antibodies that simultaneously deplete immune-blocking cells called macrophages from the surgical site and activate T cells so they can attack cancer.