Refinement of the CoroFlu vaccine concept and testing in laboratory animal models at UW–Madison is expected to take three to six months. CoroFlu could be in human clinical trials by fall, 2020.
animal research
Deleting a gene prevents Type 1 diabetes in mice by disguising insulin-producing cells
The cellular sleight of hand, says biomolecular chemist Feyza Engin, may also suggest ways to prevent other diseases in which the immune system targets the body’s own cells.
Molds damage the lung’s protective barrier to spur future asthma attacks
A UW–Madison study provides a new avenue of research for understanding and potentially preventing the development of asthma, which affects 25 million Americans.
How monkeys, mice and ferrets are helping scientists to fight coronavirus
Nature News features University of Wisconsin–Madison virologist David O’Connor on the importance of animals to learning how a virus infects cells, how the immune systems responds, and how the virus spreads to new hosts.
Researchers wake monkeys by stimulating ‘engine’ of consciousness in brain
A small amount of electricity delivered at a specific frequency to a particular point in the brain will snap a monkey out of even deep anesthesia, pointing to a circuit of brain activity key to consciousness and suggesting potential treatments for debilitating brain disorders.
UW–Madison researchers lead efforts to understand, thwart new coronavirus
Within the next few weeks, an interdisciplinary team of UW scientists hopes to begin studies of 2019-nCoV to “erect more barriers to prevent this sort of thing from happening in the future.”
Cheap nanoparticles stimulate immune response to cancer in the lab
If they are shown to work as well in the body as they do in pharmacy Professor Seungpyo Hong’s lab, the nanoparticles might provide an effective and more affordable way to fight cancer.
Flashing lights may provide vital first test of MS drug success
Measuring changes in the speed of electrical signals along nerves connecting the eyes to the brain may accurately reflect recovery from myelin loss in multiple sclerosis (MS), according to new UW-Madison research.
Injectable, flexible electrode could replace rigid nerve-stimulating implants
Neuromodulation therapies can reduce epileptic seizures, soothe chronic pain and treat depression. Now, a significant advance could dramatically reduce their cost, increase their reliability and make them much less invasive.
Common chemical linked to rare birth defect in mice
A new study reports that PBO interferes with the critical signaling pathway dubbed by scientists as sonic hedgehog, resulting in stunted forebrain development and signature facial abnormalities.