Thanks to a cutting-edge clinical trial at UW–Madison, transplant patients are returning to a healthy life without anti-rejection drugs.
News
UW oncologist studies how viruses cause cancer — and how we can better prevent them
A Q&A with Paul Lambert shows what we know about virus-linked cancers and innovative ways to limit their spread
UW researchers develop personalized cancer vaccines that slow tumor recurrence in mice
The approach could theoretically apply to any cancer that tends to recur, such as pancreatic cancer and glioblastoma, the most common and extremely aggressive brain tumor.
Could an arthritis drug unlock lasting relief from epilepsy and seizures? UW–Madison researchers see promising results in mice.
A drug typically prescribed for arthritis halts brain-damaging seizures in mice that have a condition like epilepsy, according to researchers at UW–Madison. If the drug proves viable for human patients, it would be the first to provide lasting relief from seizures even after they stopped taking it.
Human stem cell-derived heart cells are safe in monkeys, could treat congenital heart disease
Regenerating tissue to support healthy heart function could keep hearts beating stronger and longer, and this is where stem cell research is stepping in.
Brain cell grafts in monkeys jump-start human trial for new Parkinson’s treatment
People with Parkinson’s disease are receiving a new treatment in a clinical trial started after University of Wisconsin–Madison scientists demonstrated the safety and feasibility of the therapeutic delivery method in a study of non-human primates.
Studying dogs
UW–Madison researchers study animals only when there is no other way to answer important questions about the biology of complex living organisms. While dogs have made up a very small proportion of animals in studies at UW–Madison, that research has addressed important health concerns. Dogs have been vital to UW–Madison studies of cancer treatment and prevention, organ transplants, vaccines and more that have benefited both human and animal patients.
All creatures great and small: Sequencing the blue whale and Etruscan shrew genomes
Size doesn’t matter when it comes to genome sequencing in the animal kingdom, as a team of researchers at the Morgridge Institute for Research recently illustrated when assembling the sequences for two new reference genomes — one from the world’s largest mammal and one from one of the smallest.
Alzheimer’s sleep research
Researchers at the University of Wisconsin–Madison and University of Massachusetts Amherst are collaborating on a study of marmoset monkeys to learn about the role poor sleep plays in dementia and Alzheimer’s disease, debilitating disorders that often result in deadly complications. Learn more here.
Study identifies promising target for treating inflammatory bowel disease and colitis-induced colorectal cancers
Researchers uncovered a previously unknown function of a protein that is central to gut health and implicated in the development of colitis, a severe and chronic form of IBD.