Researchers uncovered a previously unknown function of a protein that is central to gut health and implicated in the development of colitis, a severe and chronic form of IBD.
Health & Wellness
Mice eating less of specific amino acid — overrepresented in diet of obese people — live longer, healthier
A calorie may not be just a calorie according to new research from the University of Wisconsin School of Medicine and Public Health.
Relieving stress in insulin-producing cells protects against Type 1 diabetes
Researchers hope that their findings, published today in the journal Cell Metabolism, may point to a potential new treatment that could be administered very early in the development of diabetes.
New drug delivery method harnesses clotting to target anti-cancer drugs at tumors
Researchers found that in mice that received the engineered proteins via intravenous injections, the proteins led to clot formation almost exclusively within tumors, with only very limited thrombosis occurring elsewhere.
UW researchers identify cell type that could be key to preventing marrow transplant complication
UW researchers at the Carbone Cancer Center have identified the cells that can cause graft-versus-host disease, the most common complication of bone marrow transplants.
New nanocapsules deliver therapy brain-wide, edit Alzheimer’s gene in mice
UW researchers have found a way to move gene therapies through the blood-brain barrier, a crucial step for brain-wide CRISPR treatments of disorders like Alzheimer’s and Parkinson’s disease.
Probiotic ‘backpacks’ show promise for treating inflammatory bowel diseases
UW researchers demonstrate just how much promise some well-equipped bacteria hold for improved inflammatory bowel disease treatments.
Brain-gut connection may reveal way to prevent cocaine addiction
Cocaine disrupts the balance of microbes in the guts of mice, part of a cycle of waxing and waning neurochemicals that can enhance the drug’s effects in the brain. But the same chemicals may also be harnessed to prevent addiction, according to new research.
Creating stem cells from minipigs offers promise for improved treatments
A new study from Wan-Ju Li’s lab in the UW–Madison Stem Cell & Regenerative Medicine Center advances research into reparative osteoarthritis therapies using stem cells derived from the ears of miniature pigs.
New understanding of ‘superantigens’ could lead to improved staph infection treatments
Researchers at the UW School of Veterinary Medicine explain that the bacterium Staphylococcus aureus not only causes illness, but undermines the body’s ability to heal — a finding that could point toward new approaches to fighting infection.